Native American education has been the focal point of her work for more than 50 years. In 1991, Rolling Stone Magazine named her as one of the ten leading professors in the nation. In 2016 Dr. Mann became one of the first two Native American educational scholars ever to be elected to membership in the National Academy of Education.
Henrietta also is sought out as a spiritual mentor and she has prayed at ceremonies ranging from Indigenous gatherings in New Zealand to Ground Zero. At 16 she enrolled at Southwestern Oklahoma State University in Weatherford and earned her Bachelor of Arts in Education degree, later earning a Master of Arts degree from Oklahoma State University, and a Doctor of Philosophy degree from the University of New Mexico.